Biozen

Phenomenex's Biozen UHPLC/HPLC columns are engineered for biologics analysis, offering biocompatible titanium BioTi™ hardware to minimize priming and ensure high sensitivity and selectivity. These columns are designed to support a wide range of applications, including:

• Charge Variant Analysis – Characterizing protein variants arising from post-translational modifications.

• Aggregate Analysis – Detecting and quantifying protein aggregates.

• Peptide Mapping – Identifying modifications and confirming primary sequences.

• Intact Mass Analysis – High-resolution mass spectrometry for protein characterization.

• Intact and Subunit Analysis – Profiling biologics at both intact and fragment levels.

• Glycan Analysis – Characterizing glycosylation patterns in monoclonal antibodies.

• Peptide Quantitation – LC-MS analysis for precise peptide concentration measurements.

• Drug Antibody Ratio (DAR) – Assessing drug-to-antibody conjugation in ADC development.

• Oligonucleotide Characterization – High-resolution separation of oligonucleotides.

These columns leverage four particle platforms and nine particle chemistries to optimize performance across different analytical needs.